Inferior Colliculus Transcriptome After Status Epilepticus in the Genetically Audiogenic Seizure-Prone Hamster GASH/Sal
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چکیده
منابع مشابه
Pharmacological and neuroethological studies of three antiepileptic drugs in the Genetic Audiogenic Seizure Hamster (GASH:Sal)
Epilepsy modeling is essential for understanding the basic mechanisms of the epileptic process. The Genetic Audiogenic Seizure Hamster (GASH:Sal) exhibits generalized tonic-clonic seizures of genetic origin in response to sound stimulation and is currently being validated as a reliable model of epilepsy. Here, we performed a pharmacological and neuroethological study using well-known and widely...
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BACKGROUND AND PURPOSE objective of our study was to determine the risk and predictive factors of status epilepticus (SE) after stroke. METHODS From 1988 to 2000, 1174 patients were admitted to the Department of Neurology at the Karadeniz Technical University Farabi Hospital with first-time strokes. Of these, 180 patients had poststroke first-time seizures (PFSs). We followed these 180 PFS pa...
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Recent evidence suggests that abnormal expression of GABA(A) receptors may underlie epileptogenesis. We observed previously that rats selectively bred to be seizure-prone naturally overexpressed, as adults, GABA alpha subunits (alpha2, alpha3, and alpha5) seen at birth, whereas those selected to be seizure-resistant overexpressed the adult, alpha1 subunit. In this experiment, we gathered GABA m...
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It has been recognized for some time that serotonin fibers originating in raphe nuclei are present in the inferior colliculi of all mammalian species studied. More recently, serotonin has been found to modulate the responses of single inferior colliculus neurons to many types of auditory stimuli, ranging from simple tone bursts to complex species-specific vocalizations. The effects of serotonin...
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Commentary Status epilepticus (SE) is a grave, life-threatening neurological emergency requiring rapid administration of definitive therapy to avoid irreversible brain injury (1), but it seems paradoxical that many children who experience it do surprisingly well. For instance, children who experience SE are no more likely to go on to develop chronic epilepsy than those who experience an ordinar...
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ژورنال
عنوان ژورنال: Frontiers in Neuroscience
سال: 2020
ISSN: 1662-453X
DOI: 10.3389/fnins.2020.00508